Chris Rock made a joke about Jada Pinkett Smith's shaved head, which did not appear to go over well with her husband Will Smith, CNN reported.
While presenting the award for best documentary, Rock joked, "Jada I love you, 'G.I. Jane 2,' can't wait to see it."
The camera cut to Pinkett Smith, who rolled her eyes as she sat next to Smith.
"That was a nice one," Rock said, appearing to respond to the joke not going over well.
Pinkett Smith has been open about her struggle with alopecia, an autoimmune disorder that leads to hair loss.
Rock then said, "Oh uh," and laughed as Smith walked toward him on stage and appeared to strike Rock in the face.
According to CNN reporter Stephanie Elam, who is in the audience, she could hear Rock getting hit. Smith said twice during the incident, according to Elam, "Keep my wife's name out of your f***ing mouth!"
Rock responded: "Oh, wow."
For viewers at home, censors muted the verbal part of the exchange between Rock and Smith.
The theater went silent and Rock said, "That was the greatest night in the history of television."
Sean "Diddy" Combs took to the stage moments later and told Smith and Rock that they would settle things "like family" later.
Photo by Getty Images
Follow NEWS.am STYLE on Facebook, Twitter and Instagram
22:19, November 11
“Men Will Do Anything for a Few Extra Inches”: BBC Documentary Exposes the Dark Side of the Penis Enlargement Industry21:21, November 11
“I Want to Be a Gentleman”: Jude Bellingham Admits He Can’t Cook or Drive20:35, November 11
Five-Year Secret Romance and a Wedding to a Georgian Opera Singer: Liechtenstein Princess Gets Married19:17, November 11
A Billion-Dollar Libido: Why the Nvidia CEO’s Alleged Romance Has Become a Matter of Global Concern16:25, November 11
Smell Like a Million Dollars for Under $50: Zara’s Affordable Alternatives to YSL, Baccarat Rouge and Tom Ford15:40, November 11
Maserati to Build a $1.1 Billion Island in Dubai: 849 Luxury Residences, Private Beaches and One Unexpected Catch15:15, November 11
Luxury for $4 Million and Four Weeks at Sea: Mercedes-Maybach Unveils an Exclusive Floating Club14:43, November 11
Max Mara Launches a New Everyday Fashion Brand With Prices Reaching $46514:16, November 11
“People Will Attack You Either Way”: Florence Pugh Opens Up About Body Shaming13:26, November 11
Dove Turns Its Iconic Soap Into a Limited-Edition Perfume for $19.5712:28, November 11
Sarah Paulson Has a Suggestion for Kim Kardashian About Her Most Controversial Underwear12:12, November 11
‘Obsessed with Sex and Attention’: Dustin Hoffman Opens Up About His Reputation as a Ladies’ Man